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This means it primarily targets growth hormone release without significantly impacting other hormones like cortisol or prolactin
Nature 462 , 739744 (2009)
While some may witness positive changes in skin tone and overall health, others may not observe significant differences
This nonselectivity underlies the potential for extracutaneous actions (e.g., overlapping with other melanocortin pathways), though MC1Rs high affinity and strong signaling efficacy make it the principal molecular target in skin and immune contexts
Think of it like turning up the brightness on your favorite photobut for your real skin
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